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High Quality Topiroxostat

  • Sep, Fri, 2020

High Quality Topiroxostat

Quick Details Port: China Main Port Payment Terms: L/C,T/T,Western Union,MoneyGram Supply Ability: 500 Kilogram/Kilograms per Month Other Names: topiroxostat Usage: Animal Pharmaceuticals Delivery time: Within 3 Days Molecular Weight: 248.24 Sample: Available Grade Standard: Medicine Grade Product Name: topiroxostat Purity: 99% Shelf life: 2 Years Appearance: White Powder CAS No.: 577778-58-6 Type: Anti-Allergic Agents Storage: Cold Dry Place Test Method: HPLC COA: Available EINECS No.: / MF: C13H8N6 Certificate: ISO Packaging Detail: 25kg/drum, 1kg/bag High Quality Topiroxostat Product Description Product Name: TopiroxostatAppearance: white powder Purity: 99.5% min Molecular formula: C13H8N6CAS: 577778-58-6Molecular weight: 248.24282 Topiroxostat is an inhibitor of xanthine oxidoreductase (IC50 = 5.3 nM), an enzyme that converts xanthine to urate. Formulations containing topiroxostat are effective in vivo, lowering urate levels in the serum of patients with hyperuricemia. In rats, but not primates, topiroxostat treatment results in the formation of xanthine crystals, resulting in nephritis. Topiroxostat also inhibits ATP-binding cassette transporter G2 (ABCG2; IC50 = 0.18 μM), a high-capacity urate transporter that functions in both renal and extrarenal urate secretion. COA   Item Specifications Results Apperance  off-white to light pink powder off-white powder Maximum single unknown Impurity ≤0.5 % 0.06% Total Impurties ≤1.0% 0.18% Loss on drying at 105℃ ≤0.5% 0.3% Purity ≥99% 99.82% Residue on ignition ≤0.5% 0.1% Conclusion The results conforms with Enterprise standards. Customer Feedback   Certifications   Company Information […]

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